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Arthritis drug Vioxx recalled
CBC News -
NEW YORK - The arthritis drug Vioxx is being pulled from the market worldwide because new research data shows it could increase the risk of heart attacks and strokes, its manufacturer announced Thursday, September 30, 2004.

A study of people enrolled in the Kaiser Permanente health plan reportedly found that heart attack rates and sudden cardiac deaths were tripled in patients taking Vioxx in doses higher than 25 milligrams a day compared to those taking a competing drug, Celebrex.

The study was done by personnel at the FDA, who said that "this and other studies cast serious doubt on the safety" of Vioxx and that Celebrex "may be safer."

There’s So Much More to Life Than Osteoarthritis Pain

If osteoarthritis pain keeps you from the activities you enjoy most, there are things you can do about it. This site is designed to help you learn about managing your pain—and to tell you about VIOXX, and CELEBREX, prescription medicine that can provide relief for osteoarthritis, the most common type of arthritis.

Spend a few minutes looking through the information provided, then discuss it with your doctor. Information about your osteoarthritis, combined with a medicine like VIOXX or CELEBREX can help make it easier to do the things you want to do.



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What to do if you are currently taking Vioxx or Celebrex?

The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.

FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.

"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.

The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.

"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."

Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.

Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.

Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.

Vioxx-Celebrex is the best way to find information about Vioxx Celebrex resources.

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VIOXX  

Important Information About VIOXX

Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart.

VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.

VIOXX should not be used by women in late pregnancy.

Talk to your doctor to learn more about VIOXX.

VIOXX -  Part 6

Osteoarthritis Pain

Why let pain force you to put the things you enjoy most on hold?

One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis symptoms to help you do the things you enjoy.

Only your healthcare provider can decide if VIOXX is right for you.

VIOXX:  Important Information:  Part 4

Vioxx may not be right for you, if you:

Have had ulcers or stomach bleeding have had asthma, hives, or allergic-type reactions after taking aspirin or other NSAIDs have severe kidney problems have severe liver problems are pregnant General Precautions with Vioxx:

Do not stop taking any medications that you have been prescribed without first talking to your doctor.

Here are some Additional
Symptom Of Temporal Arteritis Resources

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... so many different symptoms, the diagnosis of temporal arteritis can be difficult ... The most common symptoms of temporal arteritis are headache, pain in the ...
Temporal arteritis information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.
Giant cell arteritis Comprehensive overview covers symptoms, causes, treatment of this blood vessel disorder. ... temporal arteritis or cranial arteritis. ...
Temporal arteritis. Classification and external ... [edit] Symptoms ... Suspected giant cell arteritis: a study of referrals for temporal artery biopsy". Can. ...
... known as Polymyalgia Rheumatica and Temporal Arteritis. ... What Are the Symptoms of Temporal Arteritis? Temporal arteritis has several symptoms, including: ...

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Featured Vioxx Celebrex Articles

VIOXX 

Understanding Osteoarthritis

Osteoarthritis is a joint disease that gradually breaks down cartilage and bone, resulting in pain and stiffness.

It is the most common form of joint disease in the world, affecting both men and women as they grow older.

In general, osteoarthritis most often causes pain in and around fingers and weight-bearing joints, such as the feet, knees, hips, and back.

Many resources are available on the Internet to help you better understand your osteoarthritis pain. Below are links to some of these resources.

VIOXX -  Part 3

Important Information:  Special Warnings with Vioxx:

These problems can happen without any warning, but in some people may cause symptoms such as gnawing or burning stomach pain, black or tarry stools, or vomiting.

If this happens, stop taking Vioxx and call your health care provider right away.

Check with your health care provider.

VIOXX -  Part 1

Osteoarthritis Pain

There’s So Much More to Life Than Osteoarthritis Pain

If osteoarthritis pain keeps you from the activities you enjoy most, there are things you can do about it.

This site is designed to help you learn about managing your pain—and to tell you about VIOXX, a prescription medicine that can provide relief for osteoarthritis, the most common type of arthritis.

Spend a few minutes looking through the information provided, then discuss it with your doctor. Information about your osteoarthritis, combined with a medicine like VIOXX, can help make it easier to do the things you want to do.


 

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