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| Vioxx-Celebrex | Vioxx Celebrex Home > Summary Merck |
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| Vioxx-Celebrex | Vioxx Celebrex Home > Summary Merck |
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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
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Vioxx Tablet
Vioxx Vs Celebrex
Why let pain force you to put the
things you enjoy most on hold?
One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis
symptoms to help you do the things you enjoy.
Only your healthcare provider can decide if VIOXX is right for you.
Have had ulcers or stomach
bleeding have had asthma, hives, or allergic-type reactions after taking aspirin
or other NSAIDs have severe kidney problems have severe liver problems are
pregnant General Precautions with Vioxx:
Do not stop taking any medications that you have been prescribed without first
talking to your doctor.
Osteoarthritis is a joint disease that gradually breaks down cartilage and bone, resulting in pain and stiffness.
It is the most common form of joint disease in the world, affecting both men and women as they grow older.
In general, osteoarthritis most often causes pain in and around fingers and weight-bearing joints, such as the feet, knees, hips, and back.
Many resources are available on the Internet to help you better understand your osteoarthritis pain. Below are links to some of these resources.
Here are some
Additional Today's News Related To Summary Merck
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posted on November 19, 2007 10:08:10 am
Legendary value investor Jean-Marie Eveillard said ¡°To be a value investor, you have to be willing to suffer pain.¡± This is probably what a lot of value investors are experiencing. Being a lifetime value investor, he still wonders ¡°Why discipline value investing is so difficult¡±.
posted on November 16, 2007 06:50:00 am
Leading pharmaceutical companies run sleek and efficient Medical Affairs departments to reduce costs of this support function but yet truly enhance the sales and marketing function by providing instrumental input in creating winning products.
posted on November 09, 2007 11:04:23 am
CHANGE OF COURSE: Reversing its pledge to fight thousands of lawsuits individually, Merck and Co. will pay $4.85 billion to tens of thousands of Vioxx users who can show proof they...
posted on November 09, 2007 10:18:36 am
CHANGE OF COURSE: Reversing a vow to fight thousands of lawsuits individually, Merck & Co. will pay $4.85 billion to tens of thousands of Vioxx users who can show proof they suffered a heart attack or stroke.
posted on November 15, 2007 06:48:00 am
DUBLIN, Ireland----Research and Markets has announced the addition of Combating Generics 2008: Counter-Generics Strategy, Tactics and Execution to their offering.
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(This is NOT a complete list of
side effects reported with Vioxx. Your health care provider can discuss with you
a more complete list of side effects.)
Side effects can include:
Upper respiratory tract infection Diarrhea Nausea Heartburn Swelling of the
lower legs or feet High blood pressure Rarely, serious ulcers have occurred in
patients taking Vioxx.
For more detailed information about Vioxx, ask your health care provider.
Because certain other medications
can interact with Vioxx, review all medications that you are taking with your
health care provider, including those that you take without a prescription.
Your health care provider may have to adjust your dose or monitor you more
closely if you take:
certain blood pressure medications called ACE-inhibitors furosemide lithium
methotrexate rifampin warfarin aspirin Avoid taking Vioxx with antacids that
contain calcium carbonate and magnesium/aluminum combination products, because
they may reduce the amount of Vioxx your body absorbs.
Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart.
VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.
VIOXX should not be used by women in late pregnancy.
Talk to your doctor to learn more about VIOXX.
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