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| Vioxx-Celebrex | Vioxx Celebrex Home > Rofecoxib |
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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
To your right you will find links to various
Vioxx Celebrex related pages. There you will find great information about
Rofecoxib.
We've taken the time to check out each and every featured Rofecoxib website to make sure they are quality sites, with quality information.
Simply click on the links
on the RIGHT side of this page to find
some of the best resources on Rofecoxib ever compiled.
And please, be sure to check out some of our sponsored links
in the right column of this site. There you'll find some incredible resources
for Rofecoxib.
In our "Featured Rofecoxib Article" section, you'll find an article related to
Rofecoxib.
We will be providing you with updated and new featured articles on a regular
basis.
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Questions you should ask yourself when writing in the OA Pain Diary include:
What does your pain feel like? (Pain can be difficult to describe. Do your best to put it into words, such as “throbbing,” “aching,” or “stabbing.”)
When did your pain first begin, and in what part of your body?
Has it spread to other areas? Have you experienced any swelling, stiffness, or other symptoms?
Is your pain worse at certain times of the day or after certain activities?
Has anyone in your family had similar problems?
Serious problems such as liver
damage have occurred in people treated with NSAIDs.
Some of the warning signs of liver damage can be nausea, vomiting, fatigue, loss
of appetite, itching, yellow coloring of skin or eyes, "flu-like" symptoms and
dark urine.
If you experience any of these symptoms, call your health care provider right
away.
There’s So Much More to Life Than
Osteoarthritis Pain
If osteoarthritis pain keeps you from the activities you enjoy most, there are
things you can do about it.
This site is designed to help you learn about managing your pain—and to tell you
about VIOXX, a prescription medicine that can provide relief for osteoarthritis,
the most common type of arthritis.
Spend a few minutes looking through the information provided, then discuss it
with your doctor. Information about your osteoarthritis, combined with a
medicine like VIOXX, can help make it easier to do the things you want to do.
Here are some
Additional Today's News Related To Rofecoxib
Rofecoxib Resources
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posted on September 02, 2008 09:24:16 am
( European Society of Cardiology ) Since rofecoxib was withdrawn from the worldwide market based on the safety findings of the APPROVe study, the uncertainty around the cardiovascular safety of NSAIDs and COX-2 inhibitors remains and leaves practitioners with difficult management decisions for the hundreds of millions of patients worldwide who continue to require pain-relieving therapy to ...
posted on September 01, 2008 05:39:50 pm
Since Rofecoxib (Vioxx) was withdrawn from the worldwide market based on the safety findings of the Adenomatous Polyp Prevention on Vioxx (APPROVe) study, the uncertainty around the cardiovascular safety of NSAIDs and COX-2 inhibitors remains and leaves practitioners with difficult management decisions for the hundreds of millions of patients worldwide who continue to require pain-relieving ...
posted on September 03, 2008 03:41:00 pm
Ibuprofen may raise the risk of heart attacks and other fatal and serious problems when elderly people take it daily for arthritis, U.S. researchers reported on Wednesday.
posted on September 06, 2008 12:25:28 am
Osteoarthritis is the breakdown of cartilage in the joints . This is followed by chronic inflammation of the joint lining. Healthy cartilage is a cushion between the bones in a joint. Osteoarthritis usually affects the hands, feet, spine, hips, and knees.
posted on September 03, 2008 06:12:06 am
Since Rofecoxib (Vioxx) was withdrawn from the worldwide market based on the safety findings of the Adenomatous Polyp Prevention on Vioxx (APPROVe) study, the uncertainty around the cardiovascular safety of NSAIDs and COX-2 inhibitors remains and leaves practitioners with difficult management decisio
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Partnering With Your Doctor
Actively partnering with your doctor allows you to manage your osteoarthritis pain and helps your doctor make better-informed decisions about your treatment.
In this section we offer our OA Pain Diary to help you keep track of your pain episodes.
Use it to monitor your arthritis pain so both you and your doctor can get an accurate picture of any recurring patterns, changes, or new developments.
Even if your condition doesn’t change for several days, you should still note it in the diary.
Serious problems from stomach
ulcers, such as bleeding, are well-known complications in people treated with
NSAIDs.
Similar problems have occurred in people treated with Vioxx, although very
rarely.
The likelihood of stomach problems increases the longer you take drugs like
Vioxx.
However, even short-term treatment is not without risk.
In clinical studies lasting up to
21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a
significant reduction in arthritis pain. Once-daily VIOXX continued to provide
relief from pain for the length of the studies.
So VIOXX can help make it easier for you to do the things you want to do—like
sitting down on the grass to watch your kid’s soccer game—with all-day and
all-night relief.
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