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Arthritis drug Vioxx recalled
CBC News -
NEW YORK - The arthritis drug Vioxx is being pulled from the market worldwide because new research data shows it could increase the risk of heart attacks and strokes, its manufacturer announced Thursday, September 30, 2004.

A study of people enrolled in the Kaiser Permanente health plan reportedly found that heart attack rates and sudden cardiac deaths were tripled in patients taking Vioxx in doses higher than 25 milligrams a day compared to those taking a competing drug, Celebrex.

The study was done by personnel at the FDA, who said that "this and other studies cast serious doubt on the safety" of Vioxx and that Celebrex "may be safer."

There’s So Much More to Life Than Osteoarthritis Pain

If osteoarthritis pain keeps you from the activities you enjoy most, there are things you can do about it. This site is designed to help you learn about managing your pain—and to tell you about VIOXX, and CELEBREX, prescription medicine that can provide relief for osteoarthritis, the most common type of arthritis.

Spend a few minutes looking through the information provided, then discuss it with your doctor. Information about your osteoarthritis, combined with a medicine like VIOXX or CELEBREX can help make it easier to do the things you want to do.



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What to do if you are currently taking Vioxx or Celebrex?

The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.

FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.

"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.

The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.

"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."

Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.

Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.

Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.

Vioxx-Celebrex is the best way to find information about Vioxx Celebrex resources.

This web page takes the legwork out of finding great Vioxx Celebrex resources. We have compiled great links to Vioxx Celebrex information and pages dedicated to Rheumatoid Nodule here. . .

To your right you will find links to various
Vioxx Celebrex related pages. There you will find great information about Rheumatoid Nodule.

We've taken the time to check out each and every featured Rheumatoid Nodule website to make sure they are quality sites, with quality information.

Simply click on the links on the RIGHT side of this page to find some of the best resources on Rheumatoid Nodule ever compiled.

And please, be sure to check out some of our sponsored links in the right column of this site. There you'll find some incredible resources for Rheumatoid Nodule.

In our "Featured Rheumatoid Nodule Article" section, you'll find an article related to Rheumatoid Nodule.  We will be providing you with updated and new featured articles on a regular basis.

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VIOXX  - PART 1

Keeping Track of Your Pain

Questions you should ask yourself when writing in the OA Pain Diary include:

What does your pain feel like? (Pain can be difficult to describe. Do your best to put it into words, such as “throbbing,” “aching,” or “stabbing.”)

When did your pain first begin, and in what part of your body?

Has it spread to other areas? Have you experienced any swelling, stiffness, or other symptoms?

Is your pain worse at certain times of the day or after certain activities?

Has anyone in your family had similar problems?

VIOXX -  Part 5

Osteoarthritis Pain

One Pill for 24-Hour Relief

In clinical studies lasting up to 21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a significant reduction in arthritis pain. Once-daily VIOXX continued to provide relief from pain for the length of the studies.

So VIOXX can help make it easier for you to do the things you want to do—like sitting down on the grass to watch your kid’s soccer game—with all-day and all-night relief.

VIOXX -  Part 3

Important Information:  Special Warnings with Vioxx:

These problems can happen without any warning, but in some people may cause symptoms such as gnawing or burning stomach pain, black or tarry stools, or vomiting.

If this happens, stop taking Vioxx and call your health care provider right away.

Check with your health care provider.

Here are some Additional
Rheumatoid Nodule Resources

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The description of a rheumatoid nodule with photos of actual rheumatoid nodules. ... Rheumatoid Nodule of the Elbow. Photo of rheumatoid nodule of the elbow, ...
A rheumatoid nodule is a collection of normal cells including lymphocytes, and ... About 5% of rheumatoid arthritis patients have such nodules within 2 years of ...
Rheumatoid nodules may occur anywhere on the body, but are most often seen over ... Rheumatoid Nodule of the Elbow (Image) Photo of rheumatoid nodule of the ...
Online Medical Dictionary and glossary with medical definitions ... of Rheumatoid nodules. Fibromyalgia Slideshow. Rheumatoid nodules: Rheumatoid nodules are ...
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease of ... Subcutaneous rheumatoid nodules, swan-neck deformities, boutonniere deformities, ...

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    Featured Vioxx Celebrex Articles

    VIOXX  

    Partnering With Your Doctor

    Actively partnering with your doctor allows you to manage your osteoarthritis pain and helps your doctor make better-informed decisions about your treatment.

    In this section we offer our OA Pain Diary to help you keep track of your pain episodes.

    Use it to monitor your arthritis pain so both you and your doctor can get an accurate picture of any recurring patterns, changes, or new developments.

    Even if your condition doesn’t change for several days, you should still note it in the diary.

    VIOXX -  Part 5

    Osteoarthritis Pain

    One Pill for 24-Hour Relief

    In clinical studies lasting up to 21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a significant reduction in arthritis pain. Once-daily VIOXX continued to provide relief from pain for the length of the studies.

    So VIOXX can help make it easier for you to do the things you want to do—like sitting down on the grass to watch your kid’s soccer game—with all-day and all-night relief.

    VIOXX -  Part 7

    Important Information:  Vioxx may not be right for you, if you:

    If you have asthma, you may have aspirin-sensitive asthma.

    If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death.

    Since this type of reaction to aspirin and other NSAIDs have occurred in aspirin-sensitive patients, Vioxx should not be given to aspirin-sensitive patients.


     

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