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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
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Your doctor will also want to know how you are responding to the prescribed treatment.
Be sure to include in the diary any changes you may experience when you begin a treatment program or make any adjustments to it.
Why let pain force you to put the things you enjoy most on hold?
One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis symptoms to help you do the things you enjoy.
Only your healthcare provider can decide if VIOXX is right for you.
Because certain other medications
can interact with Vioxx, review all medications that you are taking with your
health care provider, including those that you take without a prescription.
Your health care provider may have to adjust your dose or monitor you more
closely if you take:
certain blood pressure medications called ACE-inhibitors furosemide lithium
methotrexate rifampin warfarin aspirin Avoid taking Vioxx with antacids that
contain calcium carbonate and magnesium/aluminum combination products, because
they may reduce the amount of Vioxx your body absorbs.
VIOXX Can Provide 24-Hour Relief
of Osteoarthritis Pain to Help You Enjoy Everyday Things Again
Managing pain isn’t about being able to climb Mount Everest or run a marathon.
It’s about controlling the pain that keeps you from doing simple things, like
taking a walk or bending down to build sand castles with your child.
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posted on October 13, 2007 01:27:39 pm
In a comparison study between schizophrenia treatments INVEGA? (paliperidone) Extended-Release Tablets and SEROQUEL® (quetiapine), Invega patients saw schizophrenia symptom improvements as early as five days into therapy and continued through the end of the two-week study period. Results were presented today at the 20th Annual U.S. Psychiatric and Mental Health Congress in Orlando, Florida. ...
posted on October 04, 2007 09:19:49 am
Dr. Andrew Weil wasn't sure exactly how he hurt his knee; all he knew was that it was painful. But instead of turning to cortisone shots or heavy doses of pain medication, Weil turned to the ancient Chinese medicine practice of acupuncture. "It worked -- my knee felt much better," says Weil.
posted on October 04, 2007 05:21:00 pm
TORONTO - Health Canada has ordered the anti-inflammatory drug Prexige off the market, citing the potential for severe liver-related side-effects.
posted on October 14, 2007 03:14:38 am
Preliminary results from a clinical study comparing INVEGA? (paliperidone) Extended-Release Tablets to quetiapine (marketed as Seroquel®) and placebo in patients with recent, acute exacerbation of schizophrenia will be the subject of a poster on display during the 20th Annual U.S. Psychiatric and Mental Health Congress, which takes place October 11-14, 2007 in Kissimmee, FL. [click link for full ...
posted on October 03, 2007 11:38:12 am
Menstruation causes monthly suffering for most women, but a variety of new treatments could offer the choice to opt out completely
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Featured Vioxx Celebrex Articles |
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Serious problems such as liver
damage have occurred in people treated with NSAIDs.
Some of the warning signs of liver damage can be nausea, vomiting, fatigue, loss
of appetite, itching, yellow coloring of skin or eyes, "flu-like" symptoms and
dark urine.
If you experience any of these symptoms, call your health care provider right
away.
Your doctor will also want to know how you are responding to the prescribed treatment.
Be sure to include in the diary any changes you may experience when you begin a treatment program or make any adjustments to it.
Why let pain force you to put the things you enjoy most on hold?
One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis symptoms to help you do the things you enjoy.
Only your healthcare provider can decide if VIOXX is right for you.
In rare cases, serious stomach
problems, such as bleeding, can occur without warning.
People with allergic reactions, such as asthma, to aspirin or other arthritis
medicines should not take VIOXX.
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