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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
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Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart.
VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.
VIOXX should not be used by women in late pregnancy. Talk to your doctor to learn more about VIOXX.
In rare cases, serious stomach
problems, such as bleeding, can occur without warning.
People with allergic reactions, such as asthma, to aspirin or other arthritis
medicines should not take VIOXX.
Vioxx can cause your body to
retain fluid and swell.
Your health care provider will decide if Vioxx is right for you, if you:
retain fluids have high blood pressure have heart failure.
Here are some
Additional Today's News Related To Information On The Drug Vioxx
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posted on November 19, 2007 04:48:51 pm
By Letter to the editor from Michael Jordan- Babbitt, Minn. I am writing in response to the Nov. 9 article in the Timberjay entitled ?Putting Patients First.? Many of the conclusions in the article, and the statements made by Joe Bianco, were inaccurate.
posted on November 15, 2007 05:35:07 pm
In a petition filed with the U.S. Food and Drug Administration, an international coalition of scientists and doctors seeks to compel the agency to stem the flood of dangerous drugs reaching American consumers by mandating the use of scientifically superior non-animal testing methods when those alternatives exist.
posted on November 20, 2007 12:20:00 am
Boston Scientific said Monday it would increase by more than 20 percent the amount the company will pay to settle thousands of patient claims involving recalled heart devices that were manufactured by a division in Arden Hills.
posted on November 14, 2007 03:08:34 pm
'Airtight' settlement of Vioxx lawsuit may have sprung a few leaks.
posted on November 12, 2007 07:43:16 pm
Merck shows how NOT to handle lawsuits. On November 9, 2007, Merck announced that it was settling approximately 27,000 lawsuits arising from the sale and distribution of Vioxx. At the time it was approved by the FDA in May 1999, Vioxx, a Cox-2 inhibitor, was hailed as a breakthrough in pain management. The data that indicated that Vioxx led to an increased chance of heart attack and...
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Vioxx Caution
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Osteoarthritis is a joint disease that gradually breaks down cartilage and bone, resulting in pain and stiffness.
It is the most common form of joint disease in the world, affecting both men and women as they grow older.
In general, osteoarthritis most often causes pain in and around fingers and weight-bearing joints, such as the feet, knees, hips, and back.
Many resources are available on the Internet to help you better understand your osteoarthritis pain. Below are links to some of these resources.
In clinical studies lasting up to
21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a
significant reduction in arthritis pain. Once-daily VIOXX continued to provide
relief from pain for the length of the studies.
So VIOXX can help make it easier for you to do the things you want to do—like
sitting down on the grass to watch your kid’s soccer game—with all-day and
all-night relief.
These problems can happen without
any warning, but in some people may cause symptoms such as gnawing or burning
stomach pain, black or tarry stools, or vomiting.
If this happens, stop taking Vioxx and call your health care provider right
away.
Check with your health care provider.
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