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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
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Acute Gouty Arthritis
Vioxx is used to relieve: Your doctor will also want to know how you are responding to the prescribed treatment. In clinical studies lasting up to
21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a
significant reduction in arthritis pain. Once-daily VIOXX continued to provide
relief from pain for the length of the studies.
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VIOXX - PART 1
Important Information:
What is Vioxx used for?
Signs and symptoms of osteoarthritis Acute pain in adults Painful menstrual
cycles.
Who should not take Vioxx?
You should not take Vioxx if you have experienced asthma, hives, or
allergic-type reactions after taking aspirin or other nonsteroidal
anti-inflammatory drugs (NSAIDs).
A few examples of other NSAIDs are ibuprofen, naproxen, diclofenac, nabumetone,
and ketoprofen.
VIOXX - PART 2
Keeping Track of Your Pain
Be sure to include in the diary any changes you may experience when you begin a treatment program or make any adjustments to it.
Why let pain force you to put the things you enjoy most on hold?
One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis symptoms to help you do the things you enjoy.
Only your healthcare provider can decide if VIOXX is right for you.VIOXX -
Part 5
Osteoarthritis Pain
One Pill for 24-Hour Relief
So VIOXX can help make it easier for you to do the things you want to do—like
sitting down on the grass to watch your kid’s soccer game—with all-day and
all-night relief.
Here are some
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posted on June 06, 2008 12:23:47 am
The Mass Audubon Long Pasture Wildlife Sanctuary, 235 Bone Hill Road in Cummaquid, will hold a series of nature-inspired Vinyasa Flow yoga classes on Wednesdays from 7 to 8 a.m. through Sept. 24. Classes are held outdoors, and all levels are welcome.
posted on June 17, 2008 06:44:23 am
Pre-Surgery Days an Opportune Time to Quit Smoking (NewsUSA) - Anyone who has had surgery or has a relative who has had surgery knows many of the pre-op drills by heart: no aspirin a week or more before surgery to prevent unnecessary bleeding, no food or drink the night before to prevent adverse reaction to anesthetics, and no jewelry in the operating room to eliminate risks of unintentional ...
posted on July 02, 2008 05:17:53 am
UCB announced that a Marketing Authorisation Application (MAA) has been submitted to the European Medicines Agency (EMEA) requesting the approval of Cimzia® (certolizumab pegol) as a subcutaneous treatment for adults with moderate to severe active rheumatoid arthritis (RA) and has been accepted for review.
posted on July 01, 2008 12:06:00 am
The European marketing authorisation application for Cimzia® has been filed. Subject to approval, Cimzia® will be the first and only PEGylated, Fc-Free anti-TNF biologic therapy.
posted on June 16, 2008 07:38:14 am
Idera Pharmaceuticals (Nasdaq: IDRA), a biopharmaceutical company focused on developing therapeutics targeting Toll-Like Receptors (TLRs), today announced the formation of an Autoimmune Disease Scientific Advisory Board.
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Featured Vioxx Celebrex Articles |
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Serious problems such as liver
damage have occurred in people treated with NSAIDs.
Some of the warning signs of liver damage can be nausea, vomiting, fatigue, loss
of appetite, itching, yellow coloring of skin or eyes, "flu-like" symptoms and
dark urine.
If you experience any of these symptoms, call your health care provider right
away.
Why let pain force you to put the
things you enjoy most on hold?
One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis
symptoms to help you do the things you enjoy.
Only your healthcare provider can decide if VIOXX is right for you.
Partnering With Your Doctor
Actively partnering with your doctor allows you to manage your osteoarthritis pain and helps your doctor make better-informed decisions about your treatment.
In this section we offer our OA Pain Diary to help you keep track of your pain episodes.
Use it to monitor your arthritis pain so both you and your doctor can get an accurate picture of any recurring patterns, changes, or new developments.
Even if your condition doesn’t change for several days, you should still note it in the diary.
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