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Arthritis drug Vioxx recalled
CBC News -
NEW YORK - The arthritis drug Vioxx is being pulled from the market worldwide because new research data shows it could increase the risk of heart attacks and strokes, its manufacturer announced Thursday, September 30, 2004.

A study of people enrolled in the Kaiser Permanente health plan reportedly found that heart attack rates and sudden cardiac deaths were tripled in patients taking Vioxx in doses higher than 25 milligrams a day compared to those taking a competing drug, Celebrex.

The study was done by personnel at the FDA, who said that "this and other studies cast serious doubt on the safety" of Vioxx and that Celebrex "may be safer."

There’s So Much More to Life Than Osteoarthritis Pain

If osteoarthritis pain keeps you from the activities you enjoy most, there are things you can do about it. This site is designed to help you learn about managing your pain—and to tell you about VIOXX, and CELEBREX, prescription medicine that can provide relief for osteoarthritis, the most common type of arthritis.

Spend a few minutes looking through the information provided, then discuss it with your doctor. Information about your osteoarthritis, combined with a medicine like VIOXX or CELEBREX can help make it easier to do the things you want to do.



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What to do if you are currently taking Vioxx or Celebrex?

The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.

FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.

"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.

The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.

"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."

Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.

Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.

Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.

Vioxx-Celebrex is the best way to find information about Vioxx Celebrex resources.

This web page takes the legwork out of finding great Vioxx Celebrex resources. We have compiled great links to Vioxx Celebrex information and pages dedicated to Exercise For People With Arthritis here. . .

To your right you will find links to various
Vioxx Celebrex related pages. There you will find great information about Exercise For People With Arthritis.

We've taken the time to check out each and every featured Exercise For People With Arthritis website to make sure they are quality sites, with quality information.

Simply click on the links on the RIGHT side of this page to find some of the best resources on Exercise For People With Arthritis ever compiled.

And please, be sure to check out some of our sponsored links in the right column of this site. There you'll find some incredible resources for Exercise For People With Arthritis.

In our "Featured Exercise For People With Arthritis Article" section, you'll find an article related to Exercise For People With Arthritis.  We will be providing you with updated and new featured articles on a regular basis.

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VIOXX -  Part 5

Osteoarthritis Pain

One Pill for 24-Hour Relief

In clinical studies lasting up to 21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a significant reduction in arthritis pain. Once-daily VIOXX continued to provide relief from pain for the length of the studies.

So VIOXX can help make it easier for you to do the things you want to do—like sitting down on the grass to watch your kid’s soccer game—with all-day and all-night relief.

VIOXX  

Partnering With Your Doctor

Actively partnering with your doctor allows you to manage your osteoarthritis pain and helps your doctor make better-informed decisions about your treatment.

In this section we offer our OA Pain Diary to help you keep track of your pain episodes.

Use it to monitor your arthritis pain so both you and your doctor can get an accurate picture of any recurring patterns, changes, or new developments.

Even if your condition doesn’t change for several days, you should still note it in the diary.

VIOXX - PART 8

Important Information:  Safety for Under Age 18

The safety and effectiveness of Vioxx in patients below the age of 18 years has not been determined.

What should I tell my doctor or health care provider?

Tell your health care provider if you are trying to become pregnant, are already pregnant, or are breast-feeding.

Here are some Additional
Exercise For People With Arthritis Resources

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Exercise can reduce pain and stiffness for those suffering from arthritis. ... Hold the position for about 15 seconds to half a minute, and then repeat with ...
INTRODUCTION Exercise is known to have benefits for people with arthritis. ... and fatigue are barriers to exercise success for many people with arthritis. ...
In persons with arthritis, exercise is safe and does not exacerbate pain or worsen disease(9-12) ... No modifications are required for people with arthritis. ...
Arthritis Exercise helps reduce pain in people with arthritis, including osteoarthritis and rheumatoid arthritis. ... Exercise is crucial for people with arthritis. ...
How Does Exercise Fit Into a Treatment Plan for People With Arthritis? ... Are There Different Exercises for People With Different Types of Arthritis? ...

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VIOXX   - PART 2

Keeping Track of Your Pain

Your doctor will also want to know how you are responding to the prescribed treatment.

Be sure to include in the diary any changes you may experience when you begin a treatment program or make any adjustments to it.

Why let pain force you to put the things you enjoy most on hold?

One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis symptoms to help you do the things you enjoy.

Only your healthcare provider can decide if VIOXX is right for you.

VIOXX -  Part 3

Osteoarthritis Pain

VIOXX can help you do the things you enjoy, with all-day, all-night relief.

One little tablet, taken just once a day, can provide 24-hour relief from osteoarthritis pain.

And VIOXX can be taken with or without food, so you don’t have to worry about scheduling it around meals.

VIOXX -  Part 7

Important Information:  Vioxx may not be right for you, if you:

If you have asthma, you may have aspirin-sensitive asthma.

If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death.

Since this type of reaction to aspirin and other NSAIDs have occurred in aspirin-sensitive patients, Vioxx should not be given to aspirin-sensitive patients.


 

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