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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
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Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart. (This is NOT a complete list of
side effects reported with Vioxx. Your health care provider can discuss with you
a more complete list of side effects.) Have had ulcers or stomach
bleeding have had asthma, hives, or allergic-type reactions after taking aspirin
or other NSAIDs have severe kidney problems have severe liver problems are
pregnant General Precautions with Vioxx:
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VIOXX
Important Information About VIOXX
VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.
VIOXX should not be used by women in late pregnancy.
Talk to your doctor to learn more about VIOXX.VIOXX -
Part 10
Important Information:
What are some possible side effects of Vioxx?
Side effects can include:
Upper respiratory tract infection Diarrhea Nausea Heartburn Swelling of the
lower legs or feet High blood pressure Rarely, serious ulcers have occurred in
patients taking Vioxx.
For more detailed information about Vioxx, ask your health care provider.VIOXX:
Important Information: Part 4
Vioxx may not be right for
you, if you:
Do not stop taking any medications that you have been prescribed without first
talking to your doctor.
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posted on November 17, 2007 12:27:29 am
Many wonder if those with fibromyalgia and chronic fatigue syndrome benefit from receiving regular massages. Read this interview with a massage therapist who specializes in fibromyalgia.
posted on November 09, 2007 03:08:21 am
Total daily dosages of milnacipran 100 mg and 200 mg demonstrated statistically significant and clinically meaningful improvements in both pain and other core symptoms associated with fibromyalgia syndrome (FMS), according to Phase III data presented this week at the 2007 American College of Rheumatology meeting in Boston, MA. [click link for full article]
posted on November 12, 2007 06:00:00 am
Fralex Therapeutics Inc. , a medical technology company developing a treatment for chronic pain associated with fibromyalgia using a non-invasive neuromodulation device, announced today its financial results for the third quarter ended September 30, 2007.
posted on November 13, 2007 02:36:05 am
Editor's note: This is the first of three columns on chronic pain. Next week's will discuss how family and friends can help.
posted on November 14, 2007 03:13:14 am
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VIOXX Can Provide 24-Hour Relief
of Osteoarthritis Pain to Help You Enjoy Everyday Things Again
Managing pain isn’t about being able to climb Mount Everest or run a marathon.
It’s about controlling the pain that keeps you from doing simple things, like
taking a walk or bending down to build sand castles with your child.
Vioxx is used to relieve: Questions you should ask yourself when writing in the OA Pain Diary include: What does your pain feel like? (Pain can be difficult to describe. Do your best to put it into words, such as “throbbing,” “aching,” or “stabbing.”)
VIOXX - PART 1
Important Information:
What is Vioxx used for?
Signs and symptoms of osteoarthritis Acute pain in adults Painful menstrual
cycles.
Who should not take Vioxx?
You should not take Vioxx if you have experienced asthma, hives, or
allergic-type reactions after taking aspirin or other nonsteroidal
anti-inflammatory drugs (NSAIDs).
A few examples of other NSAIDs are ibuprofen, naproxen, diclofenac, nabumetone,
and ketoprofen.
VIOXX - PART 1
Keeping Track of Your Pain
When did your pain first begin, and in what part of your body?
Has it spread to other areas? Have you experienced any swelling, stiffness, or other symptoms?
Is your pain worse at certain times of the day or after certain activities?
Has anyone in your family had similar problems?
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