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Arthritis drug Vioxx recalled
CBC News -
NEW YORK - The arthritis drug Vioxx is being pulled from the market worldwide because new research data shows it could increase the risk of heart attacks and strokes, its manufacturer announced Thursday, September 30, 2004.

A study of people enrolled in the Kaiser Permanente health plan reportedly found that heart attack rates and sudden cardiac deaths were tripled in patients taking Vioxx in doses higher than 25 milligrams a day compared to those taking a competing drug, Celebrex.

The study was done by personnel at the FDA, who said that "this and other studies cast serious doubt on the safety" of Vioxx and that Celebrex "may be safer."

There’s So Much More to Life Than Osteoarthritis Pain

If osteoarthritis pain keeps you from the activities you enjoy most, there are things you can do about it. This site is designed to help you learn about managing your pain—and to tell you about VIOXX, and CELEBREX, prescription medicine that can provide relief for osteoarthritis, the most common type of arthritis.

Spend a few minutes looking through the information provided, then discuss it with your doctor. Information about your osteoarthritis, combined with a medicine like VIOXX or CELEBREX can help make it easier to do the things you want to do.



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What to do if you are currently taking Vioxx or Celebrex?

The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.

FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.

"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.

The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.

"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."

Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.

Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.

Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.

Vioxx-Celebrex is the best way to find information about Vioxx Celebrex resources.

This web page takes the legwork out of finding great Vioxx Celebrex resources. We have compiled great links to Vioxx Celebrex information and pages dedicated to Arthritis Back In Symptom here. . .

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VIOXX - PART 8

Important Information:  Safety for Under Age 18

The safety and effectiveness of Vioxx in patients below the age of 18 years has not been determined.

What should I tell my doctor or health care provider?

Tell your health care provider if you are trying to become pregnant, are already pregnant, or are breast-feeding.

VIOXX   - PART 2

Keeping Track of Your Pain

Your doctor will also want to know how you are responding to the prescribed treatment.

Be sure to include in the diary any changes you may experience when you begin a treatment program or make any adjustments to it.

Why let pain force you to put the things you enjoy most on hold?

One tablet of VIOXX, once a day, can provide 24-hour relief of osteoarthritis symptoms to help you do the things you enjoy.

Only your healthcare provider can decide if VIOXX is right for you.

VIOXX -  Part 3

Osteoarthritis Pain

VIOXX can help you do the things you enjoy, with all-day, all-night relief.

One little tablet, taken just once a day, can provide 24-hour relief from osteoarthritis pain.

And VIOXX can be taken with or without food, so you don’t have to worry about scheduling it around meals.

Here are some Additional
Arthritis Back In Symptom Resources

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... symptoms of low back ... the cause of your low back pain, symptoms may be better or worse ... Symptoms caused by arthritis and symptoms due to back injury are ...
The types of back pain experienced by older adults may include increased lower back pain, stiffness in the morning and ... earliest symptoms of arthritis. ...
... of arthritis of all kinds including ankylosing spondylitis, fibromyalgia, juvenile rheumatoid arthritis, and ... arthritis.org and check back in ...
Sometimes, fighting back pain requires acting quickly and aggressively. If you have an infection, tumor of the spine or a condition called cauda equina syndrome (in ...
Watch a free how to video on Health like the "Back Arthritis Yoga Exercises" video at ExpertVillage.com. Many yoga exercises can help with arthritis pain relief...

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VIOXX -  Part 5

Osteoarthritis Pain

One Pill for 24-Hour Relief

In clinical studies lasting up to 21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a significant reduction in arthritis pain. Once-daily VIOXX continued to provide relief from pain for the length of the studies.

So VIOXX can help make it easier for you to do the things you want to do—like sitting down on the grass to watch your kid’s soccer game—with all-day and all-night relief.

VIOXX -  Part 3

Important Information:  Special Warnings with Vioxx:

These problems can happen without any warning, but in some people may cause symptoms such as gnawing or burning stomach pain, black or tarry stools, or vomiting.

If this happens, stop taking Vioxx and call your health care provider right away.

Check with your health care provider.

VIOXX  

Important Information About VIOXX

Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart.

VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.

VIOXX should not be used by women in late pregnancy. Talk to your doctor to learn more about VIOXX.


 

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