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The most important step for patients currently taking Vioxx or Celebrex is to discuss their health and history with their physician. Your doctor is hopefully aware of the potential health risks associated with these Cox-2 inhibitors and may advise using low-dose aspirin or some other alternative in order to minimize the risk of heart disease from these drugs. Patients must educate themselves on the potential risks, and if they experience any side effects associated with Cox-2 inhibitors, they need to immediately contact their doctor.
FDA: Too early to draw conclusions about Celebrex safety. Five of the 10 people who died suffered from gastrointestinal bleeding or ulcers. Of the other deaths, two were attributed to heart attacks, one to drug interaction, one to a kidney disorder--and a fifth cause remains undetermined.
"It's too early to reach any conclusions about the drug's safety," an FDA spokesman tells CNN.
The deaths and complications figured in the FDA's adverse-events report, which is filed quarterly. Reports of problems are provided by pharmaceutical companies, doctors and patients.
"There is no indication these deaths and complications were caused by the use of Celebrex," says Scarlett Foster, a spokesperson for Searle & Co., a subsidiary of Monsanto Company. "Before coming to any conclusions, we need to look at other medical conditions that could have contributed to these events."
Patient information materials provided by Searle & Co. also state stomach ulcers can occur in patients using Celebrex without the problem being evident. So patients and their doctors should watch for signs and symptoms of stomach bleeding.
Celebrex and Vioxx were approved for the U.S. market back in 1999 for the treatment of arthritis and other types of pain. Both of the drugs constituted a new class of drugs called Cox-2 inhibitors. Their release seemed to be cause for celebration for individuals who had previously taken aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs), but were bothered by gastrointestinal problems commonly associated with them.
Celebrex and Vioxx were touted as great medical developments in the many ads that promoted their benefits. Principal among these was the claim that Vioxx and Celebrex relieved pain without causing stomach problems. Specifically, these Cox-2 inhibitors are prescribed to relieve symptoms commonly associated with osteoarthritis, menstrual cramps, or other acute pain. Unfortunately, Vioxx and Celebrex pose troubling effects for some users.
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In clinical studies lasting up to
21 months, osteoarthritis patients taking 1 small tablet of VIOXX reported a
significant reduction in arthritis pain. Once-daily VIOXX continued to provide
relief from pain for the length of the studies.
So VIOXX can help make it easier for you to do the things you want to do—like
sitting down on the grass to watch your kid’s soccer game—with all-day and
all-night relief.
Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart. Serious problems from stomach
ulcers, such as bleeding, are well-known complications in people treated with
NSAIDs. VIOXX
Important Information About VIOXX
VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.
VIOXX should not be used by women in late pregnancy.
Talk to your doctor to learn more about VIOXX.
VIOXX - Part 2
Important Information:
Special Warnings with Vioxx:
Similar problems have occurred in people treated with Vioxx, although very
rarely.
The likelihood of stomach problems increases the longer you take drugs like
Vioxx.
However, even short-term treatment is not without risk.
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posted on November 15, 2007 09:51:01 am
Torture IS illegal, yet, the TV threat is trying to teach America that We, The People, haven't spoken on this issue since Law came to be. Please, I beg, please fight back for Humanity by not excepting a zionist's betrayal to G-D on this subject.
posted on November 16, 2007 08:07:00 am
Pipex Pharmaceuticals, Inc. ("Pipex"), a specialty pharmaceutical company developing innovative late-stage drug candidates for the treatment of neurologic and fibrotic diseases, announced that it has received approximately $7.3 million in gross proceeds through the exercise of warrants to purchase the Company's common stock. These warrants had been previously issued in connection with the ...
posted on November 16, 2007 11:23:42 pm
If you have a drug allergy, your immune system mistakes a medication for a disease-causing agent. A reaction to aspirin results in allergy-like symptoms but doesn't involve the immune system.
posted on November 12, 2007 01:25:30 pm
Eye care company ISTA Pharmaceuticals Inc. said Monday its ocular anti-inflammatory drug candidate Xibrom showed positive results in two late-stage clinical trials.
posted on November 16, 2007 02:21:46 pm
The pace has certainly slowed since the Vioxx recall.
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Tell your doctor if you have liver or kidney disease, or a history of angina, heart attack, or a blocked artery in your heart.
VIOXX cannot take the place of aspirin for prevention of heart attack or stroke.
VIOXX should not be used by women in late pregnancy. Talk to your doctor to learn more about VIOXX.
Have had ulcers or stomach
bleeding have had asthma, hives, or allergic-type reactions after taking aspirin
or other NSAIDs have severe kidney problems have severe liver problems are
pregnant General Precautions with Vioxx:
Do not stop taking any medications that you have been prescribed without first
talking to your doctor.
(This is NOT a complete list of
side effects reported with Vioxx. Your health care provider can discuss with you
a more complete list of side effects.)
VIOXX -
Part 10
Important Information:
What are some possible side effects of Vioxx?
Side effects can include:
Upper respiratory tract infection Diarrhea Nausea Heartburn Swelling of the
lower legs or feet High blood pressure Rarely, serious ulcers have occurred in
patients taking Vioxx.
For more detailed information about Vioxx, ask your health care provider.
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